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Efficacy of Panchakarma and Ayurvedic Herbo-mineral Preparations in the Management of Renal Cell Carcinoma with Bone Metastasis - a Case Study

Authors: Dr. Sawant Prashant M.D. (Ayu), Dr. Jagtap Reshma M.D. (Ayu.), Dr. Kadam Sandhya M.D. (Ayu), Ayurlife Positive Health Centre and Research Institute, Chembur, Mumbai - 71

Introduction:
Bone metastases in patients with renal cell carcinoma (RCC) are associated with a high risk of skeletal complications. About 40% of patients with RCC develop bone metastases. RCC is the fourth most common metastatic tumor of the spine and the most common cancer to present as a neurologic deficit secondary to an undetected primary malignancy. Chemotherapy and hormone therapy are ineffective, making radiation and surgery the mainstays of treatment. Failure to respond to or relapse after radiotherapy is common (American Journal of Neuroradiology 22:997-1003 (5 2001)

The median survival time with distant metastatic RCC is around 6 months, and few cases survive beyond 2 years. The incidence of spontaneous regression of metastatic renal cell carcinoma is thought to be less than 1% of all cases. It is reported that complete regression is even rarer than partial regression

We present a case of RCC with bone metastasis, whose bone lesions completely resolved after the ayurvedic multi-modality treatment.

Case Report:
Mr. D. S, male, age 41 years, a known case of right renal cell carcinoma (RCC) Grade II, with multiple bone metastases, approached the centre on 26/11/2004. He had complaints of severe pain in the upper back, pain in the right flank and right side of the chest over mid-axillary line, since 15 - 20 days, which increased on cough impulse. He had painful body movements and pain in the left knee joint. He also complained of cough and throat irritation.
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